Human umbilical cord mesenchymal stem cell-derived extracellular vesicles carrying miR-655-3p inhibit the development of esophageal cancer by regulating the expression of HIF-1α via a LMO4/HDAC2-dependent mechanism
Mingjiu Chen, Zhenkun Xia, Jie Deng
Topics & Concepts
Gene knockdownMesenchymal stem cellCancer researchExtracellular vesicleCellExosomeBiologyCell biologyMicrovesiclesChemistrymicroRNACell cultureGeneBiochemistryGeneticsExtracellular vesicles in diseaseMesenchymal stem cell researchMicroRNA in disease regulation