SIRT1 Activation by Polydatin Alleviates Oxidative Damage and Elevates Mitochondrial Biogenesis in Experimental Diabetic Neuropathy
Preethi Bheereddy, Veera Ganesh Yerra, Anil Kumar Kalvala, Bhoomika Sherkhane, Ashutosh Kumar
Topics & Concepts
Mitochondrial biogenesisDiabetic neuropathyMitochondrionSirtuin 1ChemistryNeuroprotectionResveratrolReactive oxygen speciesInternal medicineEndocrinologyPharmacologyStreptozotocinOxidative phosphorylationOxidative stressNeuriteDiabetes mellitusMedicineDownregulation and upregulationIn vitroBiochemistryGeneSirtuins and Resveratrol in MedicineBiochemical effects in animalsCalpain Protease Function and Regulation