Gelsevirine improves age-related and surgically induced osteoarthritis in mice by reducing STING availability and local inflammation
Meixia Feng, De-Pei Kong, Huan Guo, Chunlei Xing, Juan Lv, Huihui Bian, Nanning Lv, Chenxi Zhang, Dagui Chen, Mingming Liu, Yongsheng Yu, Li Su
Topics & Concepts
InflammationStingMedicineOsteoarthritisMMP9CartilageStimulationIn vivoPathogenesisApoptosisUbiquitinTumor necrosis factor alphaDownregulation and upregulationCancer researchPharmacologyImmunologyInternal medicineChemistryPathologyBiologyAnatomyGeneBiochemistryEngineeringAerospace engineeringAlternative medicineBiotechnologyinterferon and immune responsesCancer-related molecular mechanisms researchImmune Response and Inflammation