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Machine learning for real-time aggregated prediction of hospital admission for emergency patients

Zella King, Joseph Farrington, Martin Utley, Enoch Kung, Samer Elkhodair, Steve Harris, Richard Sekula, Jonathan Gillham, Kezhi Li, Sonya Crowe

2022npj Digital Medicine72 citationsDOIOpen Access PDF

Abstract

Machine learning for hospital operations is under-studied. We present a prediction pipeline that uses live electronic health-records for patients in a UK teaching hospital's emergency department (ED) to generate short-term, probabilistic forecasts of emergency admissions. A set of XGBoost classifiers applied to 109,465 ED visits yielded AUROCs from 0.82 to 0.90 depending on elapsed visit-time at the point of prediction. Patient-level probabilities of admission were aggregated to forecast the number of admissions among current ED patients and, incorporating patients yet to arrive, total emergency admissions within specified time-windows. The pipeline gave a mean absolute error (MAE) of 4.0 admissions (mean percentage error of 17%) versus 6.5 (32%) for a benchmark metric. Models developed with 104,504 later visits during the Covid-19 pandemic gave AUROCs of 0.68-0.90 and MAE of 4.2 (30%) versus a 4.9 (33%) benchmark. We discuss how we surmounted challenges of designing and implementing models for real-time use, including temporal framing, data preparation, and changing operational conditions.

Topics & Concepts

Emergency departmentBenchmark (surveying)MedicineCoronavirus disease 2019 (COVID-19)Emergency medicineElectronic health recordTriageProbabilistic logicZip codeMedical emergencyMachine learningMetric (unit)Computer scienceArtificial intelligenceOperations managementEngineeringHealth careDatabaseInfectious disease (medical specialty)EconomicsEconomic growthPathologyGeodesyDiseaseGeographyPsychiatryEmergency and Acute Care StudiesMachine Learning in HealthcareSepsis Diagnosis and Treatment
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