DNA Engineered Lymphocyte-Based Homologous Targeting Artificial Antigen-Presenting Cells for Personalized Cancer Immunotherapy
Lele Sun, Fengyun Shen, Zijian Xiong, Yang He, Ziliang Dong, Jian Xiang, Qingyang Gu, Qunsheng Ji, Chunhai Fan, Zhuang Liu
Abstract
applications in tumor immunotherapy, and the lipid-DNA-mediated noninvasive live cell surface engineering would be a powerful tool for designing cell-based therapeutics.
Topics & Concepts
ChemistryCancer immunotherapyCell biologyChimeric antigen receptorT-cell receptorImmunotherapyT cellImmune systemCancer researchImmunologyBiologyCAR-T cell therapy researchImmunotherapy and Immune ResponsesMonoclonal and Polyclonal Antibodies Research