Synthesis and preclinical evaluation of novel 18F-labeled fibroblast activation protein tracers for positron emission tomography imaging of cancer-associated fibroblasts
Hui Zhou, Jiawei Zhong, Simin Peng, Yang Liu, Peipei Tang, Zhikai Cai, Lu Wang, Hao Xu, Kongzhen Hu
Topics & Concepts
Fibroblast activation protein, alphaChemistryIC50PharmacokineticsPositron emission tomographyFibroblastIn vitroDOTACancerMolecular biologyCancer researchNuclear medicineChelationBiochemistryPharmacologyMedicineInternal medicineBiologyOrganic chemistryPeptidase Inhibition and AnalysisCardiac Structural Anomalies and RepairRadiopharmaceutical Chemistry and Applications