Nucleophilic addition of amino acid esters to nitrilium derivatives of closo-decaborate anion
А. V. Nelyubin, I. N. Klyukin, Alexander S. Novikov, Andrey P. Zhdanov, Mikhail S. Grigoriev, К. Yu. Zhizhin, Nikolay T. Kuznetsov
Abstract
The addition of amino acid esters to [2-B10H9–NCMe]− Bu4N+ salt under mild conditions affords amidine closo-decaborates in high yields. The structure of compound (PPh4)[2-B10H9NH=C(Me)NHCH2COOEt] was elucidated by single-crystal XRD analysis.
Topics & Concepts
ChemistryNucleophilic additionNucleophileOrganic chemistryIonMedicinal chemistryCatalysisBoron Compounds in ChemistryRadioactive element chemistry and processingRadiopharmaceutical Chemistry and Applications