Litcius/Paper detail

In-silico strategies for probing chloroquine based inhibitors against SARS-CoV-2

Satyajit Beura, Prabhakar Chetti

2020Journal of Biomolecular Structure and Dynamics75 citationsDOIOpen Access PDF

Abstract

which shows better interactions for the inhibition of SARS-CoV-2 in comparison to Chloroquine and Hydroxychloroquine.Communicated by Ramaswamy H. Sarma.

Topics & Concepts

ChloroquineADMEPharmacophoreHydroxychloroquineDocking (animal)In silicoChemistryLigand (biochemistry)PharmacologyComputational biologyCoronavirus disease 2019 (COVID-19)MedicineStereochemistryBiologyDrugReceptorBiochemistryDiseaseInfectious disease (medical specialty)ImmunologyGeneNursingPathologyMalariaComputational Drug Discovery MethodsSynthesis and biological activityBioactive Compounds and Antitumor Agents