Laboratory prognostic factors for the long-term survival of multiple system atrophy
Jung Hwan Shin, Han‐Joon Kim, Chan Young Lee, Hee Jin Chang, Kyung Ah Woo, Beomseok Jeon
Abstract
To elucidate the biomarkers related to survival in multiple system atrophy(MSA), we analyzed the predictability of retrospectively collected blood markers for survival in 650 probable MSA. High absolute neutrophil count, red-cell distribution width, C-reactive protein, erythrocyte sedimentation rate, and low hemoglobin, protein, albumin, and creatinine were correlated with higher mortality in MSA. Systemic alteration in inflammation and nutritional status in the early stage are associated with higher mortality in MSA.
Topics & Concepts
Erythrocyte sedimentation rateAtrophyCreatinineInternal medicineSystemic inflammationHemoglobinRed blood cell distribution widthAlbuminC-reactive proteinMedicineSurvival ratePathologyGastroenterologyInflammationImmunologyParkinson's Disease Mechanisms and TreatmentsRNA regulation and diseaseGenetic Neurodegenerative Diseases