NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux
Yuan He, Melody Yue Zeng, Dahai Yang, Benny Motro, Gabriel Núñez
Topics & Concepts
InflammasomePyrin domainAIM2Cell biologyNLRC4EffluxChemistrySecretionSignal transducing adaptor proteinIntracellularCaspaseNLRP1Caspase 1Signal transductionBiologyBiochemistryApoptosisReceptorProgrammed cell deathInflammasome and immune disordersGout, Hyperuricemia, Uric AcidHeme Oxygenase-1 and Carbon Monoxide