A general and green fluoroalkylation reaction promoted <i>via</i> noncovalent interactions between acetone and fluoroalkyl iodides
Ting Mao, Ming-Jian Ma, Liang Zhao, De-Pu Xue, Yanbo Yu, Jiwei Gu, Chun‐Yang He
Abstract
The first example of visible light promoted fluoroalkylation reactions initiated via noncovalent interactions between acetone and fluoroalkyl iodides is presented. The reaction system features synthetic simplicity, mild reaction conditions without any photoredox catalyst, and high functional group tolerance. A wide range of substrate scopes such as alkenes, alkynes and (hetero)arenes were all compatible with the reaction system.
Topics & Concepts
AcetoneChemistrySubstrate (aquarium)CatalysisFunctional groupReaction conditionsPhotochemistryCombinatorial chemistryOrganic chemistryPolymerGeologyOceanographyFluorine in Organic ChemistryInorganic Fluorides and Related CompoundsRadical Photochemical Reactions