Litcius/Paper detail

The Sequence Read Archive: a decade more of explosive growth

Kenneth Katz, Oleg Shutov, Richard T. Lapoint, Michael Kimelman, J. Rodney Brister, Christopher D. O’Sullivan

2021Nucleic Acids Research429 citationsDOIOpen Access PDF

Abstract

The Sequence Read Archive (SRA, https://www.ncbi.nlm.nih.gov/sra/) stores raw sequencing data and alignment information to enhance reproducibility and facilitate new discoveries through data analysis. Here we note changes in storage designed to increase access and highlight analyses that augment metadata with taxonomic insight to help users select data. In addition, we present three unanticipated applications of taxonomic analysis.

Topics & Concepts

BiologyExplosive materialSequence (biology)Computational biologyEvolutionary biologyGeneticsArchaeologyHistoryResearch Data Management PracticesDigital and Traditional Archives ManagementScientific Computing and Data Management