Ligand-controlled Rh( <scp>i</scp> )-catalyzed intramolecular alkyne sila-cyclization: divergent catalysis and mechanistic studies
Wei-Ke Zhu, Jia‐Wei Si, Sui-Fang Peng, Li Li, Fei Ye, Zhenghe Xu, Li-Wen Xu
Abstract
A chemo-divergent Rh-catalyzed Si–C bond cleavage process was established for the synthesis of novel silacycles, wherein the cyclic silylmetal intermediates undergo highly efficient intramolecular sila-cyclization reactions under mild conditions.
Topics & Concepts
ChemistryAlkyneIntramolecular forceCatalysisLigand (biochemistry)Divergent synthesisCombinatorial chemistryStereochemistryOrganic chemistryReceptorBiochemistryCatalytic Alkyne ReactionsCatalytic C–H Functionalization MethodsCatalytic Cross-Coupling Reactions