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PKM2-dependent metabolic skewing of hepatic Th17 cells regulates pathogenesis of non-alcoholic fatty liver disease

Maria E. Moreno‐Fernandez, Daniel A. Giles, Jarren R. Oates, Calvin C. Chan, Michelle S. M. A. Damen, Jessica Doll, Traci E. Stankiewicz, Xiaoting Chen, Kashish Chetal, Rebekah Karns, Matthew T. Weirauch, Lindsey E. Romick‐Rosendale, Stavra A. Xanthakos, Rachel Sheridan, Sara Szabo, Amy S. Shah, Michael A. Helmrath, Thomas H. Inge, Hitesh Deshmukh, Nathan Salomonis, Senad Divanovic

2021Cell Metabolism139 citationsDOIOpen Access PDF

Topics & Concepts

Fatty liverBiologyPKM2PathogenesisCancer researchCell biologyHepatic stellate cellAlcoholic liver diseaseGlycolysisImmunologyMedicineDiseaseInternal medicineEndocrinologyMetabolismPyruvate kinaseCirrhosisLiver Disease Diagnosis and TreatmentDiabetes and associated disordersSystemic Lupus Erythematosus Research
PKM2-dependent metabolic skewing of hepatic Th17 cells regulates pathogenesis of non-alcoholic fatty liver disease | Litcius