APX-115, a pan-NADPH oxidase inhibitor, protects development of diabetic nephropathy in podocyte specific NOX5 transgenic mice
Eun Soo Lee, Hong Min Kim, Sun Hee Lee, Kyung Bong Ha, Yoon Soo Bae, Soo Jin Lee, Sung‐Hwan Moon, Eun Young Lee, Ji-Hye Lee, Choon Hee Chung
Topics & Concepts
Internal medicineEndocrinologyDiabetic nephropathyPodocinKidneyNOX4APXChemistryNADPH oxidaseMedicinePodocyteOxidative stressSuperoxide dismutaseProteinuriaNeutrophil, Myeloperoxidase and Oxidative MechanismsAdvanced Glycation End Products researchNitric Oxide and Endothelin Effects