A Comprehensive Assessment of Hepatotoxicity Induced by Engineered Nanoparticles- A Review
Subinoy Rana
Abstract
Liver is the major detoxifying centre of the body. It removes xenobiotics and their metabolites through metabolism or biliary excretion. Hepatocytes constitute 80% of total liver mass and play a major role in storage, synthesis, metabolism and redistribution of essential molecules. Liver has been known to accumulate > 90% of nanomatrerials translocated from other organs.
Topics & Concepts
XenobioticMetabolismDrug metabolismChemistryExcretionPharmacologyBiochemistryBiologyEnzymeNanoparticles: synthesis and applicationsCurcumin's Biomedical ApplicationsNigella sativa pharmacological applications