New naphthalene derivative for cost-effective AChE inhibitors for Alzheimer’s treatment: In silico identification, in vitro and in vivo validation
Fareeha Anwar, Uzma Saleem, Bashir Ahmad, Muhammad Ashraf, Atta Ur Rehman, Matheus Froeyen, Lee Yean Kee, Iskandar Abdullah, Muhammad Usman Mirza, Sarfraz Ahmad
Topics & Concepts
In vivoIn silicoAchéPharmacologyAcetylcholinesteraseEnzymeIn vitroChemistryDrugBiochemistryComputational biologyMedicineBiologyBiotechnologyGeneCholinesterase and Neurodegenerative DiseasesComputational Drug Discovery MethodsNatural Antidiabetic Agents Studies