Osteocytes autophagy mediated by mTORC2 activation controls osteoblasts differentiation and osteoclasts activities under mechanical loading
Li Gao, Gen Liu, Xiangnan Wu, Chuanzi Liu, Yiqiao Wang, Meirui Ma, Yuanyuan Ma, Zhichao Hao, Zhichao Hao
Topics & Concepts
AutophagyChemistryCell biologySclerostinOsteoblastOsteoclastDownregulation and upregulationBone remodelingEndocrinologyApoptosisSignal transductionBiochemistryBiologyIn vitroWnt signaling pathwayGeneAutophagy in Disease and TherapyBone Metabolism and DiseasesBone health and treatments