Small molecule induced toxic human-IAPP species characterized by NMR
Sarah J. Cox, Diana C. Rodriguez Camargo, Young‐Ho Lee, Romeo C. A. Dubini, Petra Rovó, Magdalena I. Ivanova, Vediappen Padmini, Bernd Reif, Ayyalusamy Ramamoorthy
Abstract
in comparison. Remarkably, CurDAc also exhibited potent fiber disaggregation for hIAPP generating a toxic oligomeric species.
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ChemistryAmyloid (mycology)CurcuminBiophysicsCalcitoninMoleculeSmall moleculeDerivative (finance)StereochemistryBiochemistryOrganic chemistryBiologyEconomicsEndocrinologyInorganic chemistryFinancial economicsAlzheimer's disease research and treatmentsCurcumin's Biomedical ApplicationsAdvanced Glycation End Products research