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Ag<sub>2</sub>Te Quantum Dots as Contrast Agents for Near-Infrared Fluorescence and Computed Tomography Imaging

Mingxia Yu, Jiaojiao Ma, Jiamei Wang, Weiguo Cai, Zheng Zhang, Ben Huang, Mengying Sun, Qingyuan Cheng, Zhiling Zhang, Dai‐Wen Pang, Zhi‐Quan Tian

2020ACS Applied Nano Materials40 citationsDOI

Abstract

Multifunctional nanoparticles hold great potential for clinical and medical research. Herein, Ag2Te QDs were applied as multifunctional contrast agents for the second near-infrared region (NIR-II) fluorescence and X-ray computed tomography (CT) imaging. In vitro and in vivo experiments demonstrated that Ag2Te QDs exhibited low toxicity and remarkable fluorescence and CT imaging contrast properties. Moreover, long-term fluorescence imaging was also achieved. These results indicated that Ag2Te QDs had great potential as multifunctional contrast agents for near-infrared fluorescence and CT imaging in clinical research.

Topics & Concepts

FluorescenceFluorescence-lifetime imaging microscopyContrast (vision)Quantum dotMaterials scienceComputed tomographyInfraredPreclinical imagingIn vivoNuclear magnetic resonanceNanotechnologyOpticsRadiologyMedicinePhysicsBiologyBiotechnologyNanoplatforms for cancer theranosticsQuantum Dots Synthesis And PropertiesNanocluster Synthesis and Applications
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