TRIM66 hastens the malignant progression of non-small cell lung cancer via modulating MMP9-mediated TGF-β/SMAD pathway
Wenyu Chen, Ye Zhang, Zhixian Fang, Weibo Qi, Yufen Xu
Topics & Concepts
SMADMMP9Cancer researchGene silencingFlow cytometryMetastasisEpithelial–mesenchymal transitionTransfectionBiologyCell growthNude mouseChemistryApoptosisDownregulation and upregulationSignal transductionCancerMolecular biologyCell biologyCell cultureGeneGeneticsBiochemistryinterferon and immune responsesCancer Mechanisms and TherapyFerroptosis and cancer prognosis