Genome-wide In Vivo CNS Screening Identifies Genes that Modify CNS Neuronal Survival and mHTT Toxicity
Mary H. Wertz, Mollie R. Mitchem, S. Sebastian Pineda, Lea J. Hachigian, Hyeseung Lee, Vanessa Lau, Alex Powers, Ruth Kulicke, Gurrein K. Madan, Medina Colic, Martine Therrien, Amanda Vernon, Victoria F. Beja-Glasser, Mudra Hegde, Fan Gao, Manolis Kellis, Traver Hart, John G. Doench, Myriam Heiman
Topics & Concepts
BiologyGeneIn vivoGenomeGeneticsToxicityNeuroscienceComputational biologyMedicineInternal medicineGenetics and Neurodevelopmental DisordersCRISPR and Genetic EngineeringMitochondrial Function and Pathology