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The implications of BRCA loss of heterozygosity (LOH) and deficient mismatch repair gene (dMMR) expression in the breast cancer of a patient with both inherited breast and ovarian cancer syndrome (BRCA2) and Lynch syndrome (MLH1)

Steven Sorscher, Katherine Ansley, Steven Delaney, Shakti Ramkissoon

2020Breast Cancer Research and Treatment11 citationsDOI

Topics & Concepts

Breast cancerLoss of heterozygosityOvarian cancerMedicineMicrosatellite instabilityCancerLynch syndromeMLH1Colorectal cancerGermline mutationDNA mismatch repairOncologyInternal medicineGenetic testingGermlineMalignancyCancer researchMutationBiologyGeneticsAlleleGeneMicrosatelliteGenetic factors in colorectal cancerBRCA gene mutations in cancerBlood disorders and treatments
The implications of BRCA loss of heterozygosity (LOH) and deficient mismatch repair gene (dMMR) expression in the breast cancer of a patient with both inherited breast and ovarian cancer syndrome (BRCA2) and Lynch syndrome (MLH1) | Litcius