The nuclear receptor THRB facilitates differentiation of human PSCs into more mature hepatocytes
Haiting Ma, Esmée de Zwaan, Yang Guo, Paloma Cejas, Prathapan Thiru, Martijn van de Bunt, Jacob Jeppesen, Sudeepa Syamala, Alessandra Dall’Agnese, Brian J. Abraham, Dongdong Fu, Carrie M. Garrett-Engele, Tong Ihn Lee, Henry W. Long, Linda G. Griffith, Richard A. Young, Rudolf Jaenisch
Topics & Concepts
BiologyEnhancerHepatocyte nuclear factor 4Cell biologyChromatinTranscription factorNuclear receptorThyroid hormone receptorXenopusHepatocyteGene expressionInduced pluripotent stem cellRegulation of gene expressionGeneMolecular biologyEmbryonic stem cellGeneticsIn vitroLiver physiology and pathologyRNA Research and SplicingGenomics and Chromatin Dynamics