1052P Genetic modification of Iovance’s TIL through TALEN-mediated knockout of PD-1 as a strategy to empower TIL therapy for cancer
Krit Ritthipichai, MSc. Maykel Pérez Machín, Alexandre Juillerat, Laurent Poirot, Maria Fardis, Cécile Chartier
Topics & Concepts
Transcription activator-like effector nucleaseMedicineTumor-infiltrating lymphocytesCancer researchGenome editingImmunotherapyImmunologyCancerBiologyInternal medicineGeneGeneticsGenomeCAR-T cell therapy researchAdvanced biosensing and bioanalysis techniquesCancer Research and Treatments