Novel NHC-coordinated ruthenium(II) arene complexes achieve synergistic efficacy as safe and effective anticancer therapeutics
Chao Chen, Chang Xu, Tongyu Li, Siming Lu, Fangzhou Luo, Hangxiang Wang
Topics & Concepts
RutheniumCisplatinChemistryApoptosisIn vitroLigand (biochemistry)IntracellularIC50Cancer researchStereochemistryCytotoxic T cellReactive oxygen speciesCarbeneMetastasisCancer cellCell cycleCancerBiochemistryReceptorChemotherapyCatalysisBiologyInternal medicineMedicineN-Heterocyclic Carbenes in Organic and Inorganic ChemistryMetal complexes synthesis and propertiesFerrocene Chemistry and Applications