Preoperative Chest CT Myosteatosis Indicates Worse Postoperative Survival in Stage 0–IIB Non–Small Cell Lung Cancer
Lea Mantz, Nathaniel D. Mercaldo, Judit Simon, Philipp Kaess, Kai Yang, Anna-Sophia Dietrich, P. Erik Tonnesen, Amelie S. Troschel, J. Peter Marquardt, Daniel A Sehi, Cylen Javidan, Jonathan H. Chung, Henning A. Gaissert, Mark K. Ferguson, Florian J. Fintelmann
Abstract
< .001, respectively). There was no evidence of an association between OS and skeletal muscle index, SAT index, and SAT density. The predictive performance (concordance) increased from 0.723 (95% CI: 0.686, 0.753) to 0.731 (95% CI: 0.692, 0.762) after including myosteatosis markers. Conclusion Increased thoracic myosteatosis markers were associated with worse OS after lobectomy or bilobectomy of stage 0-IIB NSCLC, independent of skeletal muscle index, SAT index, and SAT density, and improved OS prediction. © RSNA, 2025