Pimarane-derived diterpenoids with anti-<i>Helicobacter pylori</i> activity from the tuber of <i>Icacina trichantha</i>
Mingming Xu, Junfei Zhou, Liping Zeng, Jingchen Xu, Monday M. Onakpa, Jin‐Ao Duan, Chun‐Tao Che, Hongkai Bi, Ming Zhao
Abstract
Two novel diterpenoids and ten known analogs were obtained from the tuber of <italic>Icacina trichantha</italic>. All compounds exhibited antibacterial activity against <italic>Helicobacter pylori</italic> strains with MIC values ranging from 8 to 64 μg mL<sup>−1</sup>.
Topics & Concepts
Helicobacter pyloriChemistryStereochemistryAntibacterial activityMicrobiologyBacteriaBiologyGeneticsPhytochemistry and Bioactive CompoundsHelicobacter pylori-related gastroenterology studiesNatural product bioactivities and synthesis