Melatonin induces fat browning by transdifferentiation of white adipocytes and<i>de novo</i>differentiation of mesenchymal stem cells
Diego Salagre, Meriem Chayah, Antonio Molina‐Carballo, María‐Jesús Oliveras‐López, Antonio Muñoz‐Hoyos, Miguel Navarro‐Alarcón, Gumersindo Fernández‐Vázquez, Ahmad Agil
Abstract
differentiation. Furthermore, it promotes beige MSC adipogenesis in humans. This may contribute to the control of body weight attributed to melatonin and its metabolic benefits in human diabesity.
Topics & Concepts
TransdifferentiationMelatoninMesenchymal stem cellBrowningEndocrinologyInternal medicineBiologyCell biologyWhite (mutation)Stem cellMedicineBiochemistryGeneAdipose Tissue and MetabolismCircadian rhythm and melatoninExercise and Physiological Responses