Novel 2019 coronavirus structure, mechanism of action, antiviral drug promises and rule out against its treatment
Subramanian Boopathi, Adolfo B. Poma, P. Kolandaivel
Abstract
is essential tool to elucidate the phenomenon. The structure-based virtual screening computational approach will be used to filter the best drugs from the literature, the investigate the structural variation of COVID-19 with the interaction of the best inhibitor is a fundamental step to design new drugs and vaccines which can combat the coronavirus. This mini-review will address novel coronavirus structure, mechanism of action, and trial test of antiviral drugs in the lab and patients with COVID-19.
Topics & Concepts
OutbreakPublic healthAntiviral drugPandemicDiseaseVirologyCoronavirusDeath tollInfectious disease (medical specialty)Coronavirus disease 2019 (COVID-19)DrugMedicineDrug developmentVirusEnvironmental healthPharmacologyPathologySARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research StudiesComputational Drug Discovery Methods