Formation of potentially toxic metabolites of drugs in reactions catalyzed by human drug-metabolizing enzymes
Slobodan Rendić, F. Peter Guengerich
Topics & Concepts
Cytochrome P450EnzymeFlavin-containing monooxygenaseChemistryMonooxygenaseIsozymeBiochemistryOxidative enzymeFlavin groupDrug metabolismAldehyde oxidaseXanthine oxidasePharmacogenetics and Drug MetabolismCancer Treatment and PharmacologyDrug Transport and Resistance Mechanisms