Transcriptional and Functional Analysis of CD1c+ Human Dendritic Cells Identifies a CD163+ Subset Priming CD8+CD103+ T Cells
Pierre Bourdely, Giorgio Anselmi, Kristīne Vaivode, Rodrigo Nalio Ramos, Yoann Missolo-Koussou, Sofía Hidalgo, Jimena Tosselo, Nicolás Gonzalo Núñez, Wilfrid Richer, Anne Vincent‐Salomon, Alka Saxena, Kristie Wood, Álvaro Lladser, Eliane Piaggio, Julie Helft, Pierre Guermonprez
Abstract
tissue-resident memory T cells. Together, these findings define DC3s as a lineage of inflammatory DCs endowed with a strong potential to regulate tumor immunity.
Topics & Concepts
BiologyCell biologyCD11cPriming (agriculture)CD8Dendritic cellCytotoxic T cellImmunologyCD163Homing (biology)AntigenIn vitroMacrophagePhenotypeBiochemistryGerminationGeneEcologyBotanyImmunotherapy and Immune ResponsesT-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers