Fibroblast Activation Protein (FAP) specific PET for advanced target volume delineation in glioblastoma
Paul Windisch, Manuel Röhrich, Sebastian Regnery, Eric Tonndorf‐Martini, Thomas Held, Kristin Lang, Denise Bernhardt, Stefan Rieken, Frederik L. Giesel, Uwe Haberkorn, Jürgen Debus, Sebastian Adeberg
Abstract
Fibroblast Activation Protein (FAP)-specific Positron Emission Tomography (PET) has shown promising results in various cancers. This pilot study compares FAP-specific PET to MRI for treatment planning in 13 Glioblastoma patients. The resulting incongruent volumes could provide additional information for radiotherapy or biopsy planning.
Topics & Concepts
Fibroblast activation protein, alphaGlioblastomaPositron emission tomographyMedicineNuclear medicineRadiation therapyGliomaBiopsyCancerOncologyRadiologyCancer researchInternal medicinePeptidase Inhibition and AnalysisRadiopharmaceutical Chemistry and ApplicationsCardiac Structural Anomalies and Repair