Recent advances of near infrared inorganic fluorescent probes for biomedical applications
Fan Yang, Qingzhe Zhang, Shengyun Huang, Dongling Ma
Abstract
S-based quantum dots (QDs) and rare earth (RE) doped NPs (RENPs) that possess quite diverse optical properties and follow different emission mechanisms. This review summarizes the recent progress on material merits, synthetic routes, the rational choice of excitation in the NIR I window, NIR II/III emission optimization, and surface modification of aforementioned fluorescent probes. We also introduce the latest notable accomplishments enabled by these probes in fluorescence imaging, lifetime-based multiplexed imaging and photothermal therapy (PTT), together with a critical discussion of forthcoming challenges and perspectives for clinic use.
Topics & Concepts
Near-infrared spectroscopyFluorescenceMaterials sciencePhotothermal therapyNanotechnologyOptoelectronicsBiological imagingLaserOpticsPhysicsNanoplatforms for cancer theranosticsLuminescence and Fluorescent MaterialsNanocluster Synthesis and Applications