Mediastinal irradiation and valvular heart disease
Shivaraj Patil, Srinath‐Reddi Pingle, Khalid Shalaby, Agnes S. Kim
Abstract
Anticancer therapy has the potential to cause unwanted cardiovascular side effects. Utilization of radiation therapy to treat tumors near the heart can result in radiation-induced valvular heart disease among other cardiovascular pathologies. The aim of this review is to describe the epidemiology, pathophysiology, risk prediction, non-invasive imaging modalities and management of radiation-induced valvular heart disease with a focus on pre-operative risk assessment and contemporary treatment options.
Topics & Concepts
valvular heart diseaseMedicineRadiation therapyDiseaseModalitiesHeart diseaseCardiologyPathophysiologyInternal medicineIntensive care medicineRadiologySocial scienceSociologyCardiac Valve Diseases and TreatmentsCardiac Imaging and DiagnosticsCardiac tumors and thrombi