A Step Forward in the Fight Against Dementia—Are We There Yet?
David A. Wolk, Gil D. Rabinovici, Bradford C. Dickerson
Abstract
This Viewpoint reports on the results of the Clarity AD trial, a phase 3 randomized clinical trial of lecanemab for patients with early Alzheimer disease, in which lecanemab’s clinical efficacy was demonstrated using well-established outcome measures.
Topics & Concepts
DementiaCLARITYClinical trialDiseaseRandomized controlled trialMedicineOutcome (game theory)PsychologyIntensive care medicineInternal medicineBiologyMathematical economicsMathematicsBiochemistryAlzheimer's disease research and treatmentsPhosphodiesterase function and regulationCholinesterase and Neurodegenerative Diseases