Protein phosphatase 2A-B56γ-Drp1-Rab7 signaling axis regulates mitochondria-lysosome crosstalk to sensitize the anti-cancer therapy of hepatocellular carcinoma
Lin Che, Jia‐Shen Wu, Chi-Yu Xu, Yuxin Cai, Jinxian Lin, Ze‐Bang Du, Jiazhang Shi, Tun Han, Yu-Qiao He, Yu‐Chun Lin, Zhong‐Ning Lin
Topics & Concepts
MitophagyLysosomeCell biologyCrosstalkPINK1MitochondrionDephosphorylationCancer researchDNM1LProtein phosphatase 2ParkinBiologyAutophagyCancer cellPhosphorylationApoptosisChemistryPhosphataseCancerMitochondrial fissionMedicineBiochemistryInternal medicineParkinson's diseaseEnzymeOpticsGeneticsDiseasePhysicsAutophagy in Disease and TherapyMitochondrial Function and PathologyEndoplasmic Reticulum Stress and Disease