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H<sub>2</sub>S-releasing amphiphilic dipeptide hydrogels are potent<i>S. aureus</i>biofilm disruptors

Yun Qian, Afnan Altamimi, Shaina Yates, Santu Sarkar, Matthew Cochran, Mingjun Zhou, Nicole Levi‐Polyachenko, John B. Matson

2020Biomaterials Science35 citationsDOIOpen Access PDF

Abstract

Hydrogen sulfide (H<sub>2</sub>S) is an endogenous signaling gas, and exogenous H<sub>2</sub>S administration has the potential for promoting wound healing. Here we investigate the antimicrobial effects of H<sub>2</sub>S-releasing hydrogels in the context of burn wound healing.

Topics & Concepts

Self-healing hydrogelsDipeptideBiofilmAmphiphileChemistryMicrobiologyOligopeptidePeptideBacteriaBiochemistryBiologyPolymer chemistryOrganic chemistryPolymerCopolymerGeneticsSulfur Compounds in BiologyNeuroscience of respiration and sleepAdenosine and Purinergic Signaling
H<sub>2</sub>S-releasing amphiphilic dipeptide hydrogels are potent<i>S. aureus</i>biofilm disruptors | Litcius