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Rhodium-catalyzed C–H activation/cyclization of aryl sulfoximines with iodonium ylides towards polycyclic 1,2-benzothiazines

Gao Huang, Yujia Shan, Jin‐Tao Yu, Changduo Pan

2021Organic & Biomolecular Chemistry20 citationsDOI

Abstract

-aryl sulfoximines with iodonium ylides was developed for the first time. In this report, C-H and N-H bond functionalization was realized towards a series of tricyclic and tetracyclic sulfoximine derivatives with moderate to excellent yields under simple reaction conditions.

Topics & Concepts

RhodiumArylChemistryCatalysisBenzothiazineTricyclicMedicinal chemistrySurface modificationCombinatorial chemistryStereochemistryOrganic chemistryAlkylPhysical chemistryCatalytic C–H Functionalization MethodsSynthesis and Catalytic ReactionsCyclopropane Reaction Mechanisms
Rhodium-catalyzed C–H activation/cyclization of aryl sulfoximines with iodonium ylides towards polycyclic 1,2-benzothiazines | Litcius