Litcius/Paper detail

Natural products with 1,2-oxazine scaffold: occurrence, chemical diversity, bioactivity, synthesis, and biosynthesis

Lihong Yan, Xin Li, Bin‐Gui Wang

2023Natural Product Reports27 citationsDOI

Abstract

) in 1925, a total of 76 naturally occurring 1,2-oxazine NPs have been isolated and identified from various sources, which have attracted the attention of researchers in the field of natural product chemistry, organic synthesis, biosynthesis, and pharmacology. This review summarizes the chemical family of 1,2-oxazine NPs, focusing on their source organisms, structural diversities, chemical synthesis, and biosynthesis.

Topics & Concepts

BiosynthesisScaffoldDiversity (politics)Natural (archaeology)ChemistryCombinatorial chemistryBiochemistryBiologyComputer scienceGeneSociologyAnthropologyDatabasePaleontologyPhenothiazines and Benzothiazines Synthesis and ActivitiesSynthesis and biological activityMicrobial Natural Products and Biosynthesis