Sex differences in gray matter, white matter, and regional brain perfusion in young, healthy adults
Jessica Muer, Kaylin D. Didier, Brett Wannebo, Sophie Sanchez, Hedyeh Khademi Motlagh, Travis Haley, Katrina J. Carter, Nile F. Banks, Marlowe W. Eldridge, Ronald C. Serlin, Oliver Wieben, William G. Schrage
Abstract
MRI used to measure cerebral blood flow (CBF) in gray matter, white matter, and 68 regions in healthy men and women. This study demonstrated that CBF is 40% higher in women, the highest sex difference reported, when controlling for numerous important clinical confounders like age, smoking, menstrual cycle, comorbidities, and medications.
Topics & Concepts
Grey matterWhite matterCerebral blood flowPerfusionMagnetic resonance imagingMedicineStatistical parametric mappingInternal medicinePerfusion scanningPhysiologyConfoundingSex characteristicsCardiologyRadiologyCerebrovascular and Carotid Artery DiseasesCardiovascular Health and Disease PreventionAdvanced MRI Techniques and Applications