Litcius/Paper detail

FBXW5 acts as a negative regulator of pathological cardiac hypertrophy by decreasing the TAK1 signaling to pro-hypertrophic members of the MAPK signaling pathway

Xuejun Hui, Fengjiao Hu, Jia Liu, Changhai Li, Yang Yang, Shangzhi Shu, Peipei Liu, Fan Wang, Shuyan Li

2020Journal of Molecular and Cellular Cardiology17 citationsDOI

Topics & Concepts

Muscle hypertrophyPressure overloadPathologicalInternal medicinePhenylephrineEndocrinologySignal transductionMAPK/ERK pathwayBiologyCardiac function curveMedicineCell biologyCardiac hypertrophyHeart failureBlood pressureUbiquitin and proteasome pathwaysSignaling Pathways in DiseaseNF-κB Signaling Pathways