Dicalcium silicate microparticles modulate the differential expression of circRNAs and mRNAs in BMSCs and promote osteogenesis<i>via</i>circ_1983–miR-6931–Gas7 interaction
Wenchao Zhong, Xingyang Li, Janak L. Pathak, Liangjiao Chen, Wei Cao, Mingjing Zhu, Qianting Luo, Antong Wu, Yunxin Chen, Lingbo Yi, Manyuan Ma, Qingbin Zhang
Abstract
S-induced osteogenic differentiation of MSCs and bone defect healing. This study opens a new research stream "the role of circRNAs-mediated ceRNA-interaction in biomaterials and stem cell-based bone tissue engineering".
Topics & Concepts
ChemistryCell biologyBiophysicsSilicateMolecular biologyBiologyOrganic chemistryCircular RNAs in diseasesMicroRNA in disease regulationBiomarkers in Disease Mechanisms