Phenotypic screening with target identification and validation in the discovery and development of E3 ligase modulators
Nil Ege, Habib Bouguenina, Marianthi Tatari, Rajesh Chopra
Topics & Concepts
Drug discoveryComputational biologyUbiquitin ligasePhenotypic screeningSmall moleculeContext (archaeology)Drug developmentBiologyIdentification (biology)PhenotypeBioinformaticsDrugUbiquitinPharmacologyGeneticsGeneBotanyPaleontologyProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysMultiple Myeloma Research and Treatments