Exploration of C‐H Activation Strategies in Construction of Functionalized 2‐Aryl Benzoazoles: A Decisive Review
Steeva Sunny, Stephy Elza John, Nagula Shankaraiah
Abstract
Abstract Transition metal‐catalyzed C−H bond activation has proved to be a powerful weapon for the synthesis and functionalization of privileged class of heterocycles. The 2‐aryl benzoazole (benzothiazoles, benzoxazoles and benzimidazoles) derivatives have surfaced in the scientific community with their potential applications in medicinal chemistry, agrochemistry and material science. The contribution of C−H activation strategies towards the functionalization of relevant 2‐aryl benzoazoles has been amenable in the drug discovery process. This review envelopes a decade account of the C−H activation strategies adopted for the functionalization of 2‐aryl benzoazoles.
Topics & Concepts
ChemistrySurface modificationArylCombinatorial chemistryNanotechnologyOrganic chemistryMaterials scienceAlkylPhysical chemistryCatalytic C–H Functionalization MethodsSulfur-Based Synthesis TechniquesSynthesis and Catalytic Reactions