Pyrazolo[3,4-d]pyrimidine-based dual EGFR T790M/HER2 inhibitors: Design, synthesis, structure–activity relationship and biological activity as potential antitumor and anticonvulsant agents

Phoebe F. Lamie, Asmaa M. El-Kalaawy, N. LATIF, Laila A. Rashed, John N. Philoppes