Folate enzyme MTHFD2 links one-carbon metabolism to unfolded protein response in glioblastoma
Zhiyuan Zhu, Karrie Mei-Yee Kiang, Ning Li, Jiaxin Liu, Pingde Zhang, Lei Jin, Xiaozheng He, Shizhong Zhang, Gkk Leung
Topics & Concepts
Pentose phosphate pathwayCancer researchApoptosisUnfolded protein responseBiologyRNA interferenceMetabolic pathwayCell growthGlycolysisEnzymeRNABiochemistryGeneEndoplasmic Reticulum Stress and DiseaseFolate and B Vitamins ResearchCancer, Hypoxia, and Metabolism