Inhibition of mitochondrial ROS-mediated necroptosis by Dendrobium nobile Lindl. alkaloids in carbon tetrachloride induced acute liver injury
Siting Xian, Yonggang Yang, Nan Nan, Xiaolong Fu, Jingshan Shi, Qin Wu, Shaoyu Zhou
Topics & Concepts
NecroptosisLiver injuryCCL4Carbon tetrachlorideReactive oxygen speciesOxidative stressMitochondrionChemistryPharmacologyIn vivoHepatoprotectionBiochemistryMolecular biologyMedicineBiologyProgrammed cell deathApoptosisGlutathioneEnzymeBiotechnologyOrganic chemistryBiological and pharmacological studies of plantsMitochondrial Function and PathologyCell death mechanisms and regulation