Litcius/Paper detail

Flexible Recyclable Cellulose Paper Templated Cu‐Doped Polydopamine Membranes with Dual Enzyme‐Like Activity

Hong Li, Zhuzhu Xiong, Yi Jia, Fan Gao, Chenlei Wang, Qi Li, Junbai Li

2022Small35 citationsDOI

Abstract

The development of high-efficiency enzyme mimics is of great significance in the field of biocatalysis. However, it remains challenging to design novel enzyme mimics with multiple enzyme-like activities, excellent stability, and good reusability. Herein, a facile molecular assembly strategy to construct dialdehyde cellulose (DAC) templated Cu-doped polydopamine (DAC@PDA/Cu) membrane with dual enzyme-like activities is presented. The Schiff base bonds formed between polydopamine (PDA) and DAC can not only accelerate the adhesion of PDA thin layer but also contribute to Cu-loading and high stability of DAC@PDA/Cu membrane. Importantly, the assembled DAC@PDA/Cu membrane exhibits a remarkable catalytic activity that is superior to the natural laccase along with high stability and excellent reusability. Moreover, the DAC@PDA/Cu membrane also demonstrates peroxidase-like activity, and it is successfully applied in the sensitive detection of ascorbic acid (AA). This work will provide a new paradigm methodology for rational design and practical applications of enzyme mimics based on bioinspired molecular assemblies.

Topics & Concepts

MembraneReusabilityMaterials scienceLaccaseBiocatalysisCelluloseNanocelluloseCombinatorial chemistryTyrosinaseImmobilized enzymeAscorbic acidRational designChemical engineeringNanotechnologyEnzymeChemistryCatalysisOrganic chemistryBiochemistryComputer scienceIonic liquidProgramming languageEngineeringSoftwareFood scienceAdvanced Nanomaterials in CatalysisElectrochemical sensors and biosensorsAdvanced biosensing and bioanalysis techniques