Dehydrocostus lactone inhibits BLM-induced pulmonary fibrosis and inflammation in mice via the JNK and p38 MAPK-mediated NF-κB signaling pathways
Yue Xiong, Xiaochuan Cui, Yanjun Zhou, Gaoshang Chai, Xiufeng Jiang, Guizhi Ge, Yue Wang, Hongxu Sun, Huilian Che, Yunjuan Nie, Peng Zhao
Topics & Concepts
Pulmonary fibrosisInflammationBleomycinp38 mitogen-activated protein kinasesFibrosisCancer researchMAPK/ERK pathwayIdiopathic pulmonary fibrosisMedicineSignal transductionNF-κBIn vivoProinflammatory cytokinePharmacologyImmunologyBiologyCell biologyPathologyLungInternal medicineChemotherapyBiotechnologyInterstitial Lung Diseases and Idiopathic Pulmonary FibrosisIL-33, ST2, and ILC PathwaysEosinophilic Disorders and Syndromes